KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP1
All Species:
12.73
Human Site:
T316
Identified Species:
40
UniProt:
O15259
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15259
NP_000263.2
732
83299
T316
K
P
V
L
Q
I
N
T
V
D
V
L
T
T
M
Chimpanzee
Pan troglodytes
XP_515684
733
83523
T317
P
V
L
Q
Q
I
N
T
V
D
V
L
T
T
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532954
694
78936
T278
A
I
S
E
Q
I
N
T
V
D
V
L
T
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY53
687
77017
V271
I
S
E
Q
I
N
T
V
D
V
L
A
T
M
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419298
726
82217
T308
M
V
V
Y
E
L
D
T
V
E
I
L
A
T
M
Frog
Xenopus laevis
NP_001085200
683
78385
T271
S
S
V
D
A
L
V
T
M
G
T
I
P
S
G
Zebra Danio
Brachydanio rerio
NP_001070638
667
74543
T259
A
V
T
E
I
D
A
T
D
V
L
S
A
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782288
622
72000
A214
D
V
L
T
A
M
G
A
I
P
A
G
F
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
78.5
N.A.
72.6
N.A.
N.A.
N.A.
58.8
55.1
43.5
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
98.9
N.A.
85.5
N.A.
83.4
N.A.
N.A.
N.A.
76.2
72.4
63.6
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
73.3
N.A.
73.3
N.A.
6.6
N.A.
N.A.
N.A.
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
80
N.A.
73.3
N.A.
13.3
N.A.
N.A.
N.A.
73.3
40
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
25
0
13
13
0
0
13
13
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
13
0
13
13
0
25
38
0
0
0
0
0
% D
% Glu:
0
0
13
25
13
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
13
0
0
13
0
13
0
0
38
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
13
0
0
25
38
0
0
13
0
13
13
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
25
13
0
25
0
0
0
0
25
50
0
0
0
% L
% Met:
13
0
0
0
0
13
0
0
13
0
0
0
0
25
50
% M
% Asn:
0
0
0
0
0
13
38
0
0
0
0
0
0
0
0
% N
% Pro:
13
13
0
0
0
0
0
0
0
13
0
0
13
0
13
% P
% Gln:
0
0
0
25
38
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
13
25
13
0
0
0
0
0
0
0
0
13
0
13
0
% S
% Thr:
0
0
13
13
0
0
13
75
0
0
13
0
50
50
0
% T
% Val:
0
50
38
0
0
0
13
13
50
25
38
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _